Jürgen Burhenne Selected Research

Bosentan (Tracleer)

1/2017	Plasma Drug Concentrations in Patients with Pulmonary Arterial Hypertension on Combination Treatment.
12/2015	Dried Blood Spot Technique for the Monitoring of Ambrisentan, Bosentan, Sildenafil, and Tadalafil in Patients with Pulmonary Arterial Hypertension.
1/2013	Influence of sildenafil and tadalafil on the enzyme- and transporter-inducing effects of bosentan and ambrisentan in LS180 cells.

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Jürgen Burhenne Research Topics

Disease

15	Neoplasms (Cancer) 03/2024 - 05/2011
9	Malaria 06/2014 - 12/2004
6	Multiple Myeloma 06/2021 - 06/2014
5	Body Weight (Weight, Body) 01/2020 - 12/2004
5	Pulmonary Arterial Hypertension 09/2017 - 01/2013
4	Tuberculosis (Tuberculoses) 01/2020 - 08/2016
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2023 - 07/2020
3	Glioblastoma (Glioblastoma Multiforme) 07/2023 - 10/2015
3	Coinfection 01/2021 - 08/2016
3	Brain Neoplasms (Brain Tumor) 08/2019 - 05/2012
3	Critical Illness (Critically Ill) 09/2017 - 09/2006
3	Infections 09/2017 - 09/2006
3	Falciparum Malaria (Plasmodium falciparum Malaria) 06/2010 - 01/2005
2	COVID-19 02/2024 - 06/2020
2	Adenocarcinoma 12/2023 - 01/2023
2	Liver Diseases (Liver Disease) 03/2023 - 01/2014
2	Glioma (Gliomas) 01/2023 - 05/2011
2	Hepatitis B 01/2023 - 09/2021
2	Stroke (Strokes) 01/2022 - 01/2019
2	Ischemic Stroke 01/2022 - 01/2019
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021 - 09/2007
2	Atrial Fibrillation 01/2019 - 01/2018
2	Renal Insufficiency (Renal Failure) 09/2017 - 09/2006
2	Sarcoma (Soft Tissue Sarcoma) 08/2017 - 01/2016
2	Erectile Dysfunction 01/2016 - 12/2005
2	Aspergillosis 09/2008 - 09/2006
2	Drug-Related Side Effects and Adverse Reactions 08/2006 - 03/2004
1	Cardiotoxicity 01/2024
1	Brain Injuries (Brain Injury) 12/2023
1	Brain Diseases (Brain Disorder) 12/2023
1	Asphyxia (Suffocation) 12/2023
1	Rheumatic Diseases (Rheumatism) 12/2023
1	Chronic Disease (Chronic Diseases) 12/2023

Drug/Important Bio-Agent (IBA)

10	Voriconazole (Vfend)FDA LinkGeneric 09/2017 - 08/2006
8	Methylene Blue (Methylthioninium Chloride)FDA Link 06/2010 - 12/2004
7	Sildenafil Citrate (Viagra)FDA Link 12/2023 - 12/2005
6	Cytochrome P-450 CYP3AIBA 12/2023 - 03/2005
6	efavirenz (Sustiva)FDA Link 01/2021 - 01/2011
5	Proteins (Proteins, Gene)FDA Link 12/2023 - 03/2008
5	Rifampin (Rifampicin)FDA LinkGeneric 01/2021 - 09/2007
5	Vorinostat FDA Link 12/2019 - 08/2014
5	Phosphodiesterase 5 InhibitorsIBA 09/2017 - 01/2013
4	EnzymesIBA 01/2024 - 03/2005
4	AnticoagulantsIBA 01/2023 - 01/2018
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2021 - 05/2011
4	Bortezomib (Velcade)FDA Link 01/2019 - 06/2014
4	Tadalafil (Cialis)FDA Link 01/2017 - 01/2013
4	Antimalarials (Antimalarial Agents)IBA 06/2014 - 03/2008
4	Chloroquine (Aralen)FDA LinkGeneric 10/2006 - 12/2004
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 12/2023 - 03/2005
3	Peptides (Polypeptides)IBA 12/2023 - 02/2021
3	Cytochrome P-450 CYP3A InhibitorsIBA 12/2023 - 08/2006
3	Endothelin Receptor AntagonistsIBA 09/2017 - 12/2015
3	Bosentan (Tracleer)FDA Link 01/2017 - 01/2013
3	ambrisentan FDA Link 01/2017 - 01/2013
3	RetinoidsIBA 10/2015 - 05/2011
3	Drug CombinationsIBA 10/2006 - 01/2005
2	Cisplatin (Platino)FDA LinkGeneric 03/2024 - 04/2012
2	RNA (Ribonucleic Acid)IBA 03/2024 - 07/2009
2	Ritonavir (Norvir)FDA Link 02/2024 - 12/2023
2	AnthracyclinesIBA 01/2024 - 01/2016
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2023 - 06/2020
2	Cytostatic AgentsIBA 12/2023 - 04/2012
2	CobicistatIBA 12/2023 - 01/2021
2	Tyrosine Kinase InhibitorsIBA 10/2023 - 07/2020
2	osimertinibIBA 10/2023 - 07/2020
2	Temozolomide (Temodar)FDA LinkGeneric 07/2023 - 12/2021
2	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 03/2023 - 01/2022
2	Chlormethiazole (Clomethiazole)IBA 03/2023 - 01/2022
2	apixabanIBA 01/2023 - 01/2019
2	bulevirtideIBA 01/2023 - 09/2021
2	Antiviral Agents (Antivirals)IBA 01/2023 - 01/2011
2	Cytochrome P-450 CYP2C19IBA 02/2022 - 08/2006
2	SodiumIBA 09/2021 - 09/2006
2	Dexamethasone (Maxidex)FDA LinkGeneric 06/2021 - 10/2014
2	ceritinibIBA 03/2020 - 08/2019
2	Midazolam (Versed)FDA LinkGeneric 01/2020 - 01/2014
2	Histone Deacetylase InhibitorsIBA 12/2019 - 08/2014
2	Melphalan (Alkeran)FDA LinkGeneric 01/2019 - 10/2014
2	Cytochrome P-450 CYP2B6 (CYP2B6)IBA 11/2018 - 01/2017
2	Histone Deacetylases (Histone Deacetylase)IBA 08/2017 - 08/2014
2	CholesterolIBA 08/2016 - 03/2013
2	Vitamin A (Retinol)FDA LinkGeneric 10/2015 - 05/2012
2	Proteasome InhibitorsIBA 02/2015 - 06/2014
2	LipidsIBA 03/2013 - 05/2012
2	betadex (beta-cyclodextrin)IBA 07/2010 - 09/2006
1	Double-Stranded RNA (RNA, Double Stranded)IBA 03/2024
1	Toll-Like Receptor 3IBA 03/2024
1	nirmatrelvir and ritonavir drug combinationIBA 02/2024
1	Factor Xa InhibitorsIBA 02/2024
1	idarubicinolIBA 01/2024
1	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 01/2024
1	Serine (L-Serine)FDA Link 12/2023
1	CalciumIBA 12/2023

Therapy/Procedure

24	Therapeutics 02/2024 - 03/2004
3	Drug Therapy (Chemotherapy) 01/2023 - 10/2014
2	Highly Active Antiretroviral Therapy (HAART) 01/2020 - 08/2016
2	Renal Replacement Therapy (Therapies, Renal Replacement) 06/2010 - 09/2006
1	Induced Hypothermia 12/2023
1	Polypharmacy 12/2023